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Owi/e 5Gy#$'kdf 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 eh `%E0b} h]k$K 模型 `o295eiY(b :S_]!'H 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 %dg[ho 25-h5$s Table 1. AZ眼睛模型的定义 )X[2~E 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. _"L6mcI6 p/VVb% 光源 ],S {?!'1 $*iovam>^] 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 vno/V#e$WX ?z&%VU" rf:H$\yw 图1. 光源和提示信息使用 =3w;<1 ?'
除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 ;%^=V# H(K
PU1lDw 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 4fC:8\A nWY^?e'S 图2. 字母F光源的设定方法光 m 0vW< /B~[,ES@1 图3. 字母F在视网膜上位置点列图 *|dK1'Xr 视网膜的散射 =(D"(OsQ/ u"*DI=pwb 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 Z9+fTT HdI)Z<Krp `>)Ge](oN 图4. 视网膜朗伯散射设定 62qjU<Z 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 o!":mJy -LszaMR} qE8aX*A1/ 图5. 视网膜重点采样规格设定 bC1G5`v_D 脚本 &tAYF_} +|,4g_(j 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: #Ir?v poxF`a6e+ 图6. 用户对话框的创建与编辑 ; s/<wx-C 图7. 用户对话框编辑器 ()l3X.t,$ 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 E6 -*2U)k+ 余下的脚本计算与屈光度有关的所有参数。 zZ8 *a\ hyf
;f7`o 分析 C\GP}:[T3 ([dd)QU 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 @
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U*$xR<8v 图7. 字母F在视网膜上颜色分析 u6ULk<<\ 脚本代码 f(Of+> `{G&i\"n Option Explicit 'Remove this to enable non-dimensioned variables to be used. fyb;*hgu Pp tuXq%U Dim entity As T_ENTITY JN|6+.GG Dim op As T_OPERATION P8,Ps+ Dim mat As T_MODELMATERIAL =,#--1R7g Dim A As Double YiDO V) Dim pupilDiam As Double lbBWOx/| Dim eID As Long w&aZ 97{ Dim parID As Long Xi98:0<= Dim count As Integer _b~{/[s Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double #Or;"}P>fB Dim tlens As Double, nlens As Double )_=2lu3%{ Dim curv As Double, conic As Double nOGTeKjEJ Dim ok As Long Ptv'.<- '%QCNO/ Sub Main
<Kv$3y !B}9gT '用户输入对话框 {}$7B p Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 @a?7D;+< TextBox 220,21,40,21,.TextBox1 'default: 0 Mz(Vf1pi% Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 QkdcW>:a7 OKButton 40,91,90,21 WK>|IgK CancelButton 190,91,90,21 Yg^ &4ZF Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 d}[cX9U/ TextBox 220,49,40,21,.TextBox2 'default: 4 -SrZ^ End Dialog ;mG*Rad Dim dlg As UserDialog x?+w8jSR tbd=A]B- ok = Dialog (dlg) $ s/E}X =Xh)34q If ok=0 Then 'cancel button was pressed @owneSD qN Print "Execution cancelled." S%i^`_=Q End tNi>TkC}` End If >CqzC8JF USz~l7Xs 'Assign accommodation and pupil diameter & use defaults if field left empty ,RV
qYh(-| If dlg.TextBox1 = "" Then }aVZ\PDg A = 0 'Default accommodation ,_Z(!|
rW Else 5QMra5N k A = CDbl(dlg.TextBox1) s{Z)<n03 End If 'rcqy1-& Fz%;_%j If dlg.TextBox2 = "" Then X g6ezlW pupilDiam = 4 'Default pupil diameter y>P+"Z.K%} Else I+8n;I)]X pupilDiam = CDbl(dlg.TextBox2) 50^ux:Uv+N End If D(AH3`*|# "?I#!t%' Print " " 1`&`y%c?B Print "Accommodation = " & A & " Diopters" 69g{oo Print "Pupil Diameter = " & pupilDiam & " mm" YX0ysE*V:& 5I622d ' Calculate new parameters with accommodation { qNPhi taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness P=QxfX0B 2*|T)OA`m, Rant = 12.0 - 0.4*A 'Radius of anterior lens hH8&g%{2 CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens E7:xPNU _v,0"_" Rpost = -5.224557 + 0.2*A 'Radius of posterior lens ^,>w`8 CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens !GqFX+!Ju i}) s4%a tlens = 3.767 + 0.04*A 'Lens thickness )>iOj50n3 /T w{JO#Q nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction !(GyOAb Y}:~6`-jj 'Adjust parameters to account for accommodation Z}J5sifr <+roY" '************************************************************************* JE?rp1. 'Aqueous thickness (Position of Lens) h.jJAVPi '************************************************************************* UerbNz| eID = FindFullName( "Geometry.Arizona Eye.Lens" ) i+Z)` GetCustomElement eID, entity b(iF0U>& XcVN{6-z parID = FindFullName( "Geometry.Arizona Eye" ) 1)ue-(o5 i5VZ,E^E ' Delete any shift(s) in z D|:'|7l W count = 0 /eF@a! While GetOperationCount(eID)>count QNj]wm=mp GetOperation eID, count, op B/twak\ If op.Type="ShiftZ" Then `2mddx8 DeleteOperation eID,count s2;~FK#/ count=count-1 $%y q[$^ End If RY , <* count=count+1 ig,.>'+l Wend cb}"giXQTB "rv~I_zl 'Set new shift in Eb8pM>'qM op.Type = "ShiftZ" |&; ^?M op.val1 = taq !}(B=- op.parent = parID M3(N!xT AddOperation eID, op hyI7X7Hy Print "Set aqueous humor thickness = " & taq-0.55 FlqGexY5 IPQRdBQ '************************************************************************* *WwM"NFHDd 'Radius and conic constant of anterior lens mMAN*}`O '************************************************************************* ?:(y eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) <LHhs<M' GetConic eID, entity, curv, conic x/*lNG/ )l3Uf&v^f SetConic eID, entity, 1/Rant, CCant ;J%:DD Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant 3:)z+#Uk6 )GD7rsC`< '************************************************************************* HBlk~eZ 'Radius and conic constant of posterior lens hFrMOc& '************************************************************************* LP2~UVq eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) #@R0$x GetConic eID, entity, curv, conic F B]Y~;( $%bSRvA SetConic eID, entity, 1/Rpost, CCpost XkaREE Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost 66yw[,Y ARH~dN* C '************************************************************************* O2w-nd74U 'Lens thickness (Position of posterior lens surface) ~iL^KeAp
'************************************************************************* O)'CU1vMb f1 ; parID = FindFullName( "Geometry.Arizona Eye.Lens" ) O0 'iq^g @@65t'3S ' Delete any z-shift(s) 7sot?gF count = 0 t R^f]+Up While GetOperationCount(eID)>count cD!,ZL GetOperation eID, count, op HW@wia If op.Type="ShiftZ" Then kSAVFzUS DeleteOperation eID,count q+ax]=w count=count-1 afm\Iv[* End If (MwRe?Ih count=count+1 <kh.fu@.Q Wend ,81%8r Jw)JV~/0 'Set new z-shift {}O~tf_ op.Type = "ShiftZ" C:QB=?%; op.val1 = tlens 'VDWJTia op.parent = parID ':*H#}Br-# AddOperation eID, op R\j~X@vI Print "Set lens thickness = " & tlens 8z=#
0+0 >F/^y O '************************************************************************* ).~
" 'Lens index of refraction @8d 3 '************************************************************************* I2[U #4n eID = FindMaterial( "Lens" ) <c+.%ka GetModelMaterial eID, mat ?Ga8.0Z~KT X/5m}-6d] mat.Nd = nlens C6!F6Stn]g SetModelMaterial eID, mat oC0ndp~+& Print "Set lens index of refraction = " & nlens X\^V{v^- W06aj ~7Z '************************************************************************* fBS a8D3}` 'Pupil diameter d:kB Zrq '************************************************************************* Bf{u:TCK eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) n`Q@<op j G8;p41 'Adjust pupil diameter (trimming volume inner hole)
a_?sJ SUS=sR/N SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" VotC YJ `DM%a~^yg ' Adjust pupil location to just in front of the lens I G1];vX parID = FindFullName( "Geometry.Arizona Eye" ) ,H=k5WA4m eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) N'
hT count = 0 }b_Ob While GetOperationCount(eID)>count I8xdE(o8+ GetOperation eID, count, op %:3XYO.w- If op.Type="ShiftZ" Then _w^,j" DeleteOperation eID,count n0(Q/ count=count-1 e@D_0OZ End If HNzxFnh count=count+1 pH'_k k Wend 4XkI? l op.Type = "ShiftZ" *22Vc2[i; op.val1 = taq-0.01 Tzq@ic#!B op.parent = parID 05d0p|}, AddOperation eID, op d |17G ASqYA1p. Print "Set pupil diameter = " & pupilDiam B[b>T= -Vn#Ab_C 'Update AZ Eye subassembly Description R)NSJ-A!2 eID = FindFullName( "Geometry.Arizona Eye" ) R1];P*>%gZ GetEntity eID, entity =p5DT entity.Description = "Accommodation = " & A & "D" lQ8hY$
SetEntity eID, entity O8]e(i F!+1w(b: Update '*J+mZt N Print "DONE!" HTQZIm z8\YMr6o End Sub nFnM9
pdMK (Pc>D';{S 如果屈光度是4,光瞳直径是4,则会输出如下数据: +x]/W|5 :=Olp;+_ Accommodation = 4 Diopters X^\D"fmE. Pupil Diameter = 4 mm +_GS@)L`% Set aqueous humor thickness = 2.81 ?I+L Set anterior lens radius = 10.4 and conic constant = -2.375869 ">}6i9o Set posterior lens radius = -4.424557 and conic constant = -3.081019 W!{RJWe Set lens thickness = 3.927 C4+DZ<pE Set lens index of refraction = 1.42672 fyQOF ItM Set pupil diameter = 4 tZ_'>7) DONE! Q-7?'\h *5)UIRd VN`.*B|9[ QQ:2987619807 3FBL CD3
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