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    [技术]Arizona眼睛模型 [复制链接]

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    只看楼主 倒序阅读 楼主  发表于: 2021-10-22
    简介 n#,l&Bx  
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    人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 N* -Z Jv  
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    模型 1#u w^{n  
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    模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 0_.hU^fP  
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    Table 1. AZ眼睛模型的定义
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    在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. QyQ8M1m  
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    光源 1r4/McB  
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    多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 pP& M]'  
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    图1. 光源和提示信息使用
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    除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 <rF  
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    在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 9mm(?O~'p  
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    图2. 字母F光源的设定方法光 -/?<@*n  
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    图3. 字母F在视网膜上位置点列图
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    视网膜的散射 I-"{m/PEdg  
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    在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 _%B`Y ?I`  
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    图4. 视网膜朗伯散射设定
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    注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 A@r,A?(  
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    图5. 视网膜重点采样规格设定
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    脚本 ;;5i'h~?]J  
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    内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: @d|9(,Q  
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    图6. 用户对话框的创建与编辑
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    图7. 用户对话框编辑器
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    如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 jEIL(0_H  
    余下的脚本计算与屈光度有关的所有参数。 %#~Wk|8} Q  
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    分析 (WvA9s{/  
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    屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 XLT<,B}e  
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    图7. 字母F在视网膜上颜色分析
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    脚本代码 '>BHwc  
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    Option Explicit     'Remove this to enable non-dimensioned variables to be used. %<t/xAge  
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    Dim entity As T_ENTITY |Oe6OCPf  
    Dim op As T_OPERATION e<K=Q$U.  
    Dim mat As T_MODELMATERIAL R0[Gfq9M =  
    Dim A As Double &3V4~L1aEg  
    Dim pupilDiam As Double +8M{y D9#  
    Dim eID As Long ojri~erJE?  
    Dim parID As Long gN%R-e0  
    Dim count As Integer f&'md  
    Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double R#>E{[9  
    Dim tlens As Double, nlens As Double [aC(Ga}  
    Dim curv As Double, conic As Double tN~{Mt$-W  
    Dim ok As Long Alz#zBGb  
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    Sub Main 0/$sr;  
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        '用户输入对话框 tr Ls4o,  
        Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 vq}V0- <  
            TextBox 220,21,40,21,.TextBox1 'default: 0 ]CjODa  
            Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 SW7%SX,xM  
            OKButton 40,91,90,21 DVd/OU  
            CancelButton 190,91,90,21 aO1cd_d6x_  
            Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 W2RS G~|  
            TextBox 220,49,40,21,.TextBox2 'default: 4 P1<;:!8'  
        End Dialog |@RO&F  
        Dim dlg As UserDialog ^^m%[$nw&r  
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        ok = Dialog (dlg) 6x0>E^~  
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        If ok=0 Then    'cancel button was pressed 0^=S:~G  
            Print "Execution cancelled." \ iFE,z  
            End J0IK =Y  
        End If hf[K\aAk  
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        'Assign accommodation and pupil diameter & use defaults if field left empty zv41Yv!x}  
        If dlg.TextBox1 = "" Then $a G'.0HW  
            A = 0           'Default accommodation WKG=d]5  
        Else (<12&=WxE  
            A = CDbl(dlg.TextBox1) f] Vz!hM~  
        End If 99 [ "I:  
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        If dlg.TextBox2 = "" Then HwHI$IB  
            pupilDiam = 4   'Default pupil diameter f: R h9  
        Else cMj<k8.{  
            pupilDiam = CDbl(dlg.TextBox2) ~'ovJ46tx  
        End If sEoS|"  
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        Print " " }~7>S5  
        Print "Accommodation = " & A & " Diopters" ^/c|s!U^  
        Print "Pupil Diameter = " & pupilDiam & " mm" .D :v0Zm}m  
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        ' Calculate new parameters with accommodation ZrTq)BZ  
        taq = 0.55 + 2.97 - 0.04*A              'Aqueous thickness HV}NT~  
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        Rant = 12.0 - 0.4*A                     'Radius of anterior lens Z1Ms ~tch  
        CCant = -7.518749 + 1.285720*A          'Conic constant of anterior lens E_++yK^=  
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        Rpost = -5.224557 + 0.2*A               'Radius of posterior lens T/H*Bo *=5  
        CCpost = -1.353971 - 0.431762*A         'Conic constant of posterior lens BjA|H  
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        tlens = 3.767 + 0.04*A                  'Lens thickness 8w{V[@QLn  
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        nlens = 1.42 + 0.00256*A - 0.00022*A^2  'Lens index of refraction '!_o`t@  
    9`xq3EL2T  
        'Adjust parameters to account for accommodation 3}"VUS0wh  
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        '************************************************************************* toF@@ %  
        'Aqueous thickness (Position of Lens) k2xjcrg  
        '************************************************************************* LE7o[<>  
        eID = FindFullName( "Geometry.Arizona Eye.Lens" ) a@%FwfIu  
        GetCustomElement eID, entity qB8<(vBP+  
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        parID = FindFullName( "Geometry.Arizona Eye" ) Cnn,$R=/s  
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        ' Delete any shift(s) in z _8bqk\m+  
        count = 0 ~sM334sQ  
        While GetOperationCount(eID)>count lY6U$*9c  
            GetOperation eID, count, op 5~\W!|j/  
            If op.Type="ShiftZ" Then 2+|[e_  
                DeleteOperation eID,count ;N)qNiJY  
                count=count-1 $hA[vi\5  
            End If 5 bgx;z9  
            count=count+1 n |(Y?`(  
        Wend _3)~{dQ+  
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        'Set new shift in _N<8!(|w  
        op.Type = "ShiftZ" >:Rc%ILym  
        op.val1 = taq `/0FXb 8h  
        op.parent = parID -1fT2e  
        AddOperation eID, op AR&u9Y)I  
        Print "Set aqueous humor thickness = " & taq-0.55 ,#s}nJ4  
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        '************************************************************************* %R}}1  
        'Radius and conic constant of anterior lens PyIIdTm  
        '************************************************************************* >ztv3^w  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) ,UY],;ib  
        GetConic eID, entity, curv, conic (;!&RZ  
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        SetConic eID, entity, 1/Rant, CCant O%rjY  
        Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant X.g1 312~  
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        '************************************************************************* n`}vcVL;  
        'Radius and conic constant of posterior lens si)920?E&  
        '************************************************************************* la f b^  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) Zsaz#z|xW  
        GetConic eID, entity, curv, conic i/~A7\:8%  
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        SetConic eID, entity, 1/Rpost, CCpost Dk/;`sXV  
        Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost vX&Nh"0H&  
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        '************************************************************************* {G_ZEo#x8,  
        'Lens thickness (Position of posterior lens surface) K o,O!T.  
        '************************************************************************* =p$1v{L8  
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        parID = FindFullName( "Geometry.Arizona Eye.Lens" ) FhW\23OC  
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        ' Delete any z-shift(s) 7)z^*;x  
        count = 0 EZao\,t  
        While GetOperationCount(eID)>count s-Bpd#G>/  
            GetOperation eID, count, op L= hPu#&/  
            If op.Type="ShiftZ" Then Q!MS_ #O  
                DeleteOperation eID,count Q R;Xj3]v  
                count=count-1 $GEY*uIOa  
            End If ,{7Z OzA  
            count=count+1 v-EcJj%  
        Wend B xq(+^T  
     GVe[)R  
        'Set new z-shift E\5t&jZr  
        op.Type = "ShiftZ" f8!*4Bw  
        op.val1 = tlens F:1w%#6av  
        op.parent = parID #D&eov?  
        AddOperation eID, op +,f|Y6L<  
        Print "Set lens thickness = " & tlens g7rn|<6FI  
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        '************************************************************************* W/L~&.'  
        'Lens index of refraction hxGZ}zq*S  
        '************************************************************************* ):31!IC  
        eID = FindMaterial( "Lens" ) .e~17}Ka}  
        GetModelMaterial eID, mat q0&g.=;  
    :[?hU}9  
        mat.Nd = nlens :iP2e+j  
        SetModelMaterial eID, mat C0Z mv  
        Print "Set lens index of refraction = " & nlens a^>0XXr}Y  
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        '************************************************************************* |1uyJ?%B  
        'Pupil diameter 2c LIz@  
        '************************************************************************* B ;@7  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) k|'{$/ n  
    +:+q,0~*]  
        'Adjust pupil diameter (trimming volume inner hole) =`Pgo5A  
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        SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" Q,S~+bD(z  
    ozy~`$;c  
        ' Adjust pupil location to just in front of the lens Ko|nF-r_  
        parID = FindFullName( "Geometry.Arizona Eye" ) wsYvbI!  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) ~7IXJeon  
        count = 0 Q$^oIFb  
        While GetOperationCount(eID)>count e3oHe1"hP  
            GetOperation eID, count, op yY_Zq\   
            If op.Type="ShiftZ" Then Z9,-FO{#3-  
                DeleteOperation eID,count %F_)!M;x  
                count=count-1 xp7 `[.  
            End If rozp  
            count=count+1 | vL0}e  
        Wend NitsUg@<  
        op.Type = "ShiftZ" 4+"2K-]   
        op.val1 = taq-0.01 GH[ATL  
        op.parent = parID eg!s[1[_  
        AddOperation eID, op lA>^k;+>  
    &c>%E%!"  
        Print "Set pupil diameter = " & pupilDiam "H\1Z,P<m  
    ]-]K4*{   
        'Update AZ Eye subassembly Description 0h=NbLr|S-  
        eID = FindFullName( "Geometry.Arizona Eye" ) yq]=+X>(  
        GetEntity eID, entity jMr[ UZ  
        entity.Description = "Accommodation = " & A & "D" kCRfO}wt3  
        SetEntity eID, entity UEHJ? }  
    }@6ws/5  
        Update [@ >}  
        Print "DONE!" >%LZ|*U  
         q(xr5iuP_  
    End Sub HueGARS  
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    如果屈光度是4,光瞳直径是4,则会输出如下数据: S\5%nz \  
    x# MMrV&M  
    Accommodation = 4 Diopters 0])D)%B k  
    Pupil Diameter = 4 mm j}u b  
    Set aqueous humor thickness = 2.81 X\&CQiPS  
    Set anterior lens radius = 10.4 and conic constant = -2.375869 7W[+e&  
    Set posterior lens radius = -4.424557 and conic constant = -3.081019  qHVZsZ  
    Set lens thickness = 3.927 e7tp4M9!%  
    Set lens index of refraction = 1.42672 pY.R?\  
    Set pupil diameter = 4 +;,65j+n   
    DONE! dmA#v:$1  
     
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