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简介 @jMo/kO/A }wvR s5;o 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 ts@$* ;R2A>f~ 模型 ?f'`b<o 8$47Y2r@ 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 L[*cbjt[ mrG?5.7W Table 1. AZ眼睛模型的定义 ]:?S}DRG 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd.
2~g-k3 :R:@V#Y 光源 is^R8a Oe@w$? 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 PZZPx<?N 7SYe:^Dx |4j6}g\ 图1. 光源和提示信息使用 S[/udA 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 $t"QLsk0 O_th/hl 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 wG)[Ik6: cyHbAtl 图2. 字母F光源的设定方法光 i(.PkYkaq b3%a4Gg& 图3. 字母F在视网膜上位置点列图 r^rk@W;[ 视网膜的散射 pG)dF@ k$J!,!q 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 eS
?9}TG| z4(\yx Wrp+B[{r\ 图4. 视网膜朗伯散射设定 udr|6EjD. 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 *,O3@,+>H <GQ=PrT|/ $qZ6i 图5. 视网膜重点采样规格设定 ZK'WKC 脚本 OT|0_d?bD )*uo tV 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: $/#[,1 +=|%9% 图6. 用户对话框的创建与编辑 4o@:+T:1 图7. 用户对话框编辑器 z+wegF 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 a+k3wzJ 余下的脚本计算与屈光度有关的所有参数。 Y|hd!C-x
tIod=a) 分析 ^
.A oPbziB8 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 ~/aCzx~ KY%qzq,n 图7. 字母F在视网膜上颜色分析 MuzQz.C 脚本代码 =c&.I}^1L 7!Im|7Ty Option Explicit 'Remove this to enable non-dimensioned variables to be used. XA. 1Y) FrLv%tK| Dim entity As T_ENTITY 'BgR01w J Dim op As T_OPERATION ""N~##)8 Dim mat As T_MODELMATERIAL /#eS3`48 Dim A As Double E|_8#xvb Dim pupilDiam As Double
gy|o#&e]% Dim eID As Long /6y{?0S Dim parID As Long !a!4^zqp Dim count As Integer 3N2d@R Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double xy&*s\=: Dim tlens As Double, nlens As Double $X\2h+ Os Dim curv As Double, conic As Double ZzR0k Dim ok As Long L|-|DOgw `}$bJCSF.n Sub Main aAn p7\7 Z:x`][vg '用户输入对话框 x6Gl|e[jv Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 368 g>/#' TextBox 220,21,40,21,.TextBox1 'default: 0 hV)
`e"r\s Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 tBl(E OKButton 40,91,90,21 z?|bs?HKS CancelButton 190,91,90,21 )g3c-W= Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 P (Y\l TextBox 220,49,40,21,.TextBox2 'default: 4 s+&0Z3+ End Dialog /"~UGn]R Dim dlg As UserDialog t pxk8Ys .VUnOdI ok = Dialog (dlg) S-7 C'dc RVs=s}|>* If ok=0 Then 'cancel button was pressed Clap3E|a Print "Execution cancelled." 2 1+[9 End Qr6PkHU End If V
joVC$ZX WW^+X~Y 'Assign accommodation and pupil diameter & use defaults if field left empty 7xG~4N<)] If dlg.TextBox1 = "" Then 7<B-2g A = 0 'Default accommodation hK{<&T Else mZM7 4!4X A = CDbl(dlg.TextBox1) f3>DmH# End If H5UF r,t c"1Z,M;G If dlg.TextBox2 = "" Then @+y,E-YTdV pupilDiam = 4 'Default pupil diameter vO/ 3bu} Else YZtd IG pupilDiam = CDbl(dlg.TextBox2) |*-<G3@ End If WoNY8
8hT D$NpyF.87 Print " " *{Z=)k% Print "Accommodation = " & A & " Diopters" ,LmP >Q. Print "Pupil Diameter = " & pupilDiam & " mm" Wa&!1'
@ AUIp
vd
' Calculate new parameters with accommodation %@TC-
xx taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness aS\$@41" i*!2n1c[ Rant = 12.0 - 0.4*A 'Radius of anterior lens |pq9i)e& CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens WA:r4V n:k4t Rpost = -5.224557 + 0.2*A 'Radius of posterior lens SQx&4R. CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens n;>=QG
-v QH,(iX6RY tlens = 3.767 + 0.04*A 'Lens thickness ` QW=<Le? MQ0rln? nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction L2~'Z'q nf1 `)tXG 'Adjust parameters to account for accommodation O.xtY@'" I:UDEoQo '************************************************************************* iy]?j$B$ 'Aqueous thickness (Position of Lens) @_#\qGY '************************************************************************* rcY &n^: eID = FindFullName( "Geometry.Arizona Eye.Lens" ) <l5m\A GetCustomElement eID, entity #V#!@@c;? wArfnB& parID = FindFullName( "Geometry.Arizona Eye" ) AS;qJ)JfzQ ijzwct#. ' Delete any shift(s) in z C4|OsC7J count = 0 wp>
z04
While GetOperationCount(eID)>count rK:cUW0]X GetOperation eID, count, op 'U0W If op.Type="ShiftZ" Then RU~ku{8? DeleteOperation eID,count uhp.Yv@c count=count-1 ;/JXn End If LNHi}P~ count=count+1 \^RKb-6n Wend _5x]BH6f :g^
mg-8 'Set new shift in BHZhdm@), op.Type = "ShiftZ" <1<xSr op.val1 = taq WjM7s]ZRv op.parent = parID .q[}e);) AddOperation eID, op ylQj2B,CB Print "Set aqueous humor thickness = " & taq-0.55 `<M>"~W
uKvdL
" '*************************************************************************
P +OS 'Radius and conic constant of anterior lens :Q@/F;Z? '************************************************************************* {P_7AM eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) yTZo4c" GetConic eID, entity, curv, conic )c'E9ZuZ>d h8(>$A- SetConic eID, entity, 1/Rant, CCant < *;GJ{ Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant #(i
pF RtpV08s\ '************************************************************************* (K84J*; 'Radius and conic constant of posterior lens `.3@Ki~$# '************************************************************************* ?2dI8bG eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) 4K?
\5(b GetConic eID, entity, curv, conic CS(2bj^6D hh*('n>[ SetConic eID, entity, 1/Rpost, CCpost jC{KI!kPt Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost &);P|v`8 NVsaV;u '************************************************************************* u'>94Gm} 'Lens thickness (Position of posterior lens surface) 5r~jo7 '************************************************************************* !jSgpIp 6pbCQ
q parID = FindFullName( "Geometry.Arizona Eye.Lens" ) @DY"~ccH ubOXEkZ8N ' Delete any z-shift(s) UXJblo# count = 0 cBZEyy& While GetOperationCount(eID)>count y1Z>{SDiq GetOperation eID, count, op DZnqCu"J If op.Type="ShiftZ" Then xy"'8uRi DeleteOperation eID,count X:;x5'| count=count-1 HK~SD:d End If bE'{zU}o count=count+1 ::$W
.!Uv Wend [3nWxFz$R $[,4Ib_| 'Set new z-shift dpylJ2 op.Type = "ShiftZ" vO~Tx op.val1 = tlens O#=%t op.parent = parID *qk7e[IP AddOperation eID, op ThI}~$Y Print "Set lens thickness = " & tlens "#E<Leh' LR>s2zu- '************************************************************************* f pq|mY 'Lens index of refraction ftR& 5!Wm '************************************************************************* G:tY1'5 eID = FindMaterial( "Lens" ) 'hs4k|B GetModelMaterial eID, mat 4YikC .O5V;&, mat.Nd = nlens -9,~b9$ SetModelMaterial eID, mat s_VcC_A Print "Set lens index of refraction = " & nlens jga \Ry=nw Bps%>P~. '************************************************************************* mY4pvpZw8 'Pupil diameter L-D4>+ '************************************************************************* _avf%OS eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) xn503,5G*7 ~nfOV* 'Adjust pupil diameter (trimming volume inner hole) ~h; -kMw[Y SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" "IT7.!=@9 2(@2z[eKr ' Adjust pupil location to just in front of the lens ka\{?:r,8 parID = FindFullName( "Geometry.Arizona Eye" ) N\g=9o|Q eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) rD SYR\cg count = 0 *S:~U While GetOperationCount(eID)>count <a @7's GetOperation eID, count, op Z6i~Dy3 If op.Type="ShiftZ" Then Z}uY%] DeleteOperation eID,count 4hwb]
Yz count=count-1 5 k3m"* End If ge
GhM>G count=count+1 :#^qn|{e Wend NOXP}M op.Type = "ShiftZ" ZxwrlaA op.val1 = taq-0.01 s~A-qG> op.parent = parID 208^Yu AddOperation eID, op 8e*skL S1U0sP@o Print "Set pupil diameter = " & pupilDiam 4F#H$`:[ @`4T6eL5 'Update AZ Eye subassembly Description S7f.^8 eID = FindFullName( "Geometry.Arizona Eye" ) VbvP!<8 GetEntity eID, entity _90D4kGU entity.Description = "Accommodation = " & A & "D" w>^(w<~Y SetEntity eID, entity \j`0f=z_ BA2"GJvfIA Update HdqB B Print "DONE!" {k_\1t(/ &`l\Q\_[@ End Sub [:cD bt) C+|i 如果屈光度是4,光瞳直径是4,则会输出如下数据: :
"|/ *O~y6|U? Accommodation = 4 Diopters <.n,:ir Pupil Diameter = 4 mm 9,INyEyAL Set aqueous humor thickness = 2.81 rz%~=Ca2j Set anterior lens radius = 10.4 and conic constant = -2.375869 )-)rL@s. Set posterior lens radius = -4.424557 and conic constant = -3.081019 x:MwM? Set lens thickness = 3.927 Jq&Hz$L| Set lens index of refraction = 1.42672 yogavCD9b/ Set pupil diameter = 4 $45|^.b DONE! ?pW1}:z
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