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    [技术]Arizona眼睛模型 [复制链接]

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    离线infotek
     
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    只看楼主 倒序阅读 楼主  发表于: 2021-10-22
    简介 YQ; cJ$  
    =4eUAeH {w  
    人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 :4|M jn  
    AIb>pL{  
    模型 m+?N7  
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    模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 C\7u<2c  
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    Table 1. AZ眼睛模型的定义
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    在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. N#4N?BBP"  
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    光源 `ruNA>M  
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    多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 t-WjL@$F/  
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    图1. 光源和提示信息使用
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    除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 k'Gw!p}  
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    在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 B@ {&<  
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    图2. 字母F光源的设定方法光 9t?L\  
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    图3. 字母F在视网膜上位置点列图
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    视网膜的散射 eJHp6)2  
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    在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 >.e+S?o  
    6W&_2a7*  
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    图4. 视网膜朗伯散射设定
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    注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 ,X68xk.'  
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    图5. 视网膜重点采样规格设定
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    脚本 F)S PaC4  
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    内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: je%ldY]/@  
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    图6. 用户对话框的创建与编辑
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    图7. 用户对话框编辑器
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    如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 'H|~u&?  
    余下的脚本计算与屈光度有关的所有参数。 w^HjZV  
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    分析 [ ny6W9  
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    屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 M&KyA  
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    图7. 字母F在视网膜上颜色分析
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    脚本代码 8md*wEjk  
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    Option Explicit     'Remove this to enable non-dimensioned variables to be used. +&5' uAe  
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    Dim entity As T_ENTITY bcH_V| 5}  
    Dim op As T_OPERATION ^:KO_{3E  
    Dim mat As T_MODELMATERIAL I[d]!YI}F  
    Dim A As Double Xj@+{uvQB  
    Dim pupilDiam As Double DMn4ll|  
    Dim eID As Long  &;c>O  
    Dim parID As Long 7 ^$;  
    Dim count As Integer TTZe$>f  
    Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double QR0(,e$Dl  
    Dim tlens As Double, nlens As Double XRtD< jlA"  
    Dim curv As Double, conic As Double qf#)lyr<D6  
    Dim ok As Long ]*N1t>fb  
    ^YlI>_3s  
    Sub Main lG:kAtx4  
    .c+9P<VmC}  
        '用户输入对话框 -SCM:j%h  
        Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 S,{tV=&m]  
            TextBox 220,21,40,21,.TextBox1 'default: 0 Am"(+>W21  
            Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 S,jZ3^  
            OKButton 40,91,90,21 n V&cC  
            CancelButton 190,91,90,21 t;NV $!!  
            Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 ny*i+4Mb  
            TextBox 220,49,40,21,.TextBox2 'default: 4 vScjq5 "p  
        End Dialog F<|t\KOW  
        Dim dlg As UserDialog 5,)vJ,fs  
    "_1)CDqP  
        ok = Dialog (dlg) k N7Bd}  
    %*}Y6tl'|  
        If ok=0 Then    'cancel button was pressed h6:#!Rg  
            Print "Execution cancelled." *ZrSiIPP  
            End uLR<FpM  
        End If B?bW1  
    aZS7sV28  
        'Assign accommodation and pupil diameter & use defaults if field left empty g>JLDQdc  
        If dlg.TextBox1 = "" Then 78 f$6J q  
            A = 0           'Default accommodation -NJ!g/ >mM  
        Else 9+=gke  
            A = CDbl(dlg.TextBox1) bulS&dAX  
        End If i3$$,W!  
    r6Aneg7  
        If dlg.TextBox2 = "" Then W?woNt'n  
            pupilDiam = 4   'Default pupil diameter XvTCK>1  
        Else Z4b||  
            pupilDiam = CDbl(dlg.TextBox2) }H> ^o9  
        End If [iP#VM-N  
    zi@]83SS#  
        Print " " 64>krmVIe  
        Print "Accommodation = " & A & " Diopters" ]=pR  
        Print "Pupil Diameter = " & pupilDiam & " mm" X}ma]  
    R%Y`=pK>}  
        ' Calculate new parameters with accommodation ]6r;}1c  
        taq = 0.55 + 2.97 - 0.04*A              'Aqueous thickness ]`g@UtD9`  
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        Rant = 12.0 - 0.4*A                     'Radius of anterior lens 6w8" >~)Z  
        CCant = -7.518749 + 1.285720*A          'Conic constant of anterior lens MGS-4>Q#  
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        Rpost = -5.224557 + 0.2*A               'Radius of posterior lens ZBT1Y.qA  
        CCpost = -1.353971 - 0.431762*A         'Conic constant of posterior lens Zdc63fllM  
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        tlens = 3.767 + 0.04*A                  'Lens thickness m0n)dje  
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        nlens = 1.42 + 0.00256*A - 0.00022*A^2  'Lens index of refraction Z<[<n0o1  
    bNs4 5hDP  
        'Adjust parameters to account for accommodation @mP]*$00  
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        '************************************************************************* O/s $SX%g  
        'Aqueous thickness (Position of Lens) :}8Z@H!KkY  
        '************************************************************************* afBE{  
        eID = FindFullName( "Geometry.Arizona Eye.Lens" ) IYn]U4P.  
        GetCustomElement eID, entity \MC-4Yz  
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        parID = FindFullName( "Geometry.Arizona Eye" ) R0ID2:i]F  
    ,2Q o7(A  
        ' Delete any shift(s) in z !* Ti}oIo&  
        count = 0 zi R5:d3   
        While GetOperationCount(eID)>count M>9-=$7  
            GetOperation eID, count, op o1W:ox?kO  
            If op.Type="ShiftZ" Then R'EUV0KX>Y  
                DeleteOperation eID,count %,Sf1fUJ  
                count=count-1 U$]|~41#  
            End If 00v&lQBW  
            count=count+1 Vtc36-\1*  
        Wend ?Nf>]|K:Q  
    ]D[DU]K  
        'Set new shift in !tfb*@{;'  
        op.Type = "ShiftZ" 0"2=n.##  
        op.val1 = taq {~!q`Dr3?q  
        op.parent = parID F <>!kK/c  
        AddOperation eID, op r.3/F[.  
        Print "Set aqueous humor thickness = " & taq-0.55 S5~VD?O,  
    f` =CpO*  
        '************************************************************************* Gj"7s8(/K|  
        'Radius and conic constant of anterior lens (?_S6H E  
        '************************************************************************* ];.pK  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) &j(+/;A  
        GetConic eID, entity, curv, conic Ox#\M0Wn$3  
    O"Ku1t!  
        SetConic eID, entity, 1/Rant, CCant _^Mx>hb4.  
        Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant *Qugv^-  
    q0f3="  
        '************************************************************************* ST\$=  
        'Radius and conic constant of posterior lens ,'[<bP'%_  
        '************************************************************************* (WJ${OW  
        eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) .>Ljnk  
        GetConic eID, entity, curv, conic TIp:FW[  
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        SetConic eID, entity, 1/Rpost, CCpost 'cY` w  
        Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost n6s}ww)  
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        '************************************************************************* XsnF~)YW  
        'Lens thickness (Position of posterior lens surface) ,%\o4Rc'o  
        '************************************************************************* fS~;>n%R  
    :_!8 WB  
        parID = FindFullName( "Geometry.Arizona Eye.Lens" ) /~x "wo  
    =-_B:d;  
        ' Delete any z-shift(s) 5:'hj$~|\1  
        count = 0 R|wGU)KEc'  
        While GetOperationCount(eID)>count K|dso]b/  
            GetOperation eID, count, op 0eK*9S]  
            If op.Type="ShiftZ" Then %Gt .m  
                DeleteOperation eID,count z5)s/;Sc  
                count=count-1 v|U(+O  
            End If (SKVuR%Jj  
            count=count+1 os/vtyP:a  
        Wend 0GJn_@hr  
    ]T%rjsN  
        'Set new z-shift T49zcJf;  
        op.Type = "ShiftZ" zN  [2YJ$  
        op.val1 = tlens 6/rFHY2q  
        op.parent = parID cJ54s}  
        AddOperation eID, op lP<:tR~K  
        Print "Set lens thickness = " & tlens NH+(?TN  
    y~)1 1]'>  
        '************************************************************************* *zr(Zv  
        'Lens index of refraction N^3N[lD{  
        '************************************************************************* !?|Th5e   
        eID = FindMaterial( "Lens" ) {mAU3x  
        GetModelMaterial eID, mat o7|eMe?<t  
    V0)fZS@tf  
        mat.Nd = nlens qi_Jywd:w  
        SetModelMaterial eID, mat OF\rgz  
        Print "Set lens index of refraction = " & nlens I'|$}/\`  
    qAw x2fPu  
        '************************************************************************* U"Zmv  
        'Pupil diameter vd8{c7g:n  
        '************************************************************************* )E~ 79!  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) L'F<ev  
    XGl+S  
        'Adjust pupil diameter (trimming volume inner hole) u9N 1pZ~  
    ^Vpq$'!  
        SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" b,C aWg  
    *hw\35%P`?  
        ' Adjust pupil location to just in front of the lens J>\B`E  
        parID = FindFullName( "Geometry.Arizona Eye" ) ub|V\M{  
        eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) f"<O0Qw  
        count = 0 ~$~5qwl  
        While GetOperationCount(eID)>count B'fb^n<  
            GetOperation eID, count, op K"r*M.P>  
            If op.Type="ShiftZ" Then kXf'5p1  
                DeleteOperation eID,count a[ex[TRKe  
                count=count-1 gSh+}r<7  
            End If d+'p@!W_  
            count=count+1 0zi~p>*nJC  
        Wend l(02W  
        op.Type = "ShiftZ" +(h\fm7*-  
        op.val1 = taq-0.01 5F~'gLH/F-  
        op.parent = parID 7x@A%2J  
        AddOperation eID, op Bro9YP4<  
    :53)N v  
        Print "Set pupil diameter = " & pupilDiam 62Z#Y Q}x  
    _ A=$oVe  
        'Update AZ Eye subassembly Description R=|{n'n$0|  
        eID = FindFullName( "Geometry.Arizona Eye" ) sD=n95`v  
        GetEntity eID, entity $g sxO!G  
        entity.Description = "Accommodation = " & A & "D" 8|" XSN  
        SetEntity eID, entity :3I@(k\PY  
    <"_d]?,  
        Update O<,\^[x  
        Print "DONE!" \ioH\9  
         ` eXaT8  
    End Sub Pqn@ST  
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    如果屈光度是4,光瞳直径是4,则会输出如下数据: &sU?Ok6  
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    Accommodation = 4 Diopters #Jw1IcuH  
    Pupil Diameter = 4 mm =W"F[fD  
    Set aqueous humor thickness = 2.81 pim!.=vN/U  
    Set anterior lens radius = 10.4 and conic constant = -2.375869 2n|K5FR()  
    Set posterior lens radius = -4.424557 and conic constant = -3.081019 i{`;R  
    Set lens thickness = 3.927 /\hzb/  
    Set lens index of refraction = 1.42672 D8xmE2%  
    Set pupil diameter = 4 6E^.7%3  
    DONE! D/Mi^5H)  
     
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