FRED运用:Arizona眼睛模型
简介 V|2[>\Cv 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 ~qE:Nz0@ Q^'xVS_. 模型 CSzu$Hnq pWeD,!f 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 p3IhK> Vzh\1cF
Table 1. AZ眼睛模型的定义 [attachment=67931] m*14n_m' 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. $L72%T LO,:k+&A+ 光源 Hr(%y&0 7\i> > 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 $F@ ,,* AZ.
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[attachment=67932] 图1. 光源和提示信息使用 `Js"*[z 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 [n$6T SM.KM_%K 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 fHgvh&FU p%+'iDb
[attachment=67933] 图2. 字母F光源的设定方法光 we33GMxHl` 4=l$wg~;
[attachment=67934] 图3. 字母F在视网膜上位置点列图 mfk^t`w_ 视网膜的散射 gAK"ShOhG= 5?>ES* 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 (J.U{N v *$Z?Owl7 L1MG("R
[attachment=67935] 图4. 视网膜朗伯散射设定 GjX6noqT 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 D1wONss 55zy]|F" N@I=X-7nh|
[attachment=67936] 图5. 视网膜重点采样规格设定 +DYsBCVbag 脚本 ]9}^}U1." |0VZ1{=* 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: $AdBX}{ H
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[attachment=67937] 图6. 用户对话框的创建与编辑 ZtX
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[attachment=67938] 图7. 用户对话框编辑器 RVh{wg 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 Ed1y%mR> 余下的脚本计算与屈光度有关的所有参数。 7DWGYvv[ PeJIa
%iE 分析 -7VQ{nC 3qy4nPg 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 2k^'}7G% MAL;XcRR
[attachment=67939] 图7. 字母F在视网膜上颜色分析 ULzrJbP'7 脚本代码 $-paYQ4 9`7>"[=P Option Explicit 'Remove this to enable non-dimensioned variables to be used. bv}e[yH )h0b}HMW) Dim entity As T_ENTITY qTe@?j Dim op As T_OPERATION wotw nE Dim mat As T_MODELMATERIAL U.N?cKv Dim A As Double 0CK3jdZ+X Dim pupilDiam As Double #GzowI' Dim eID As Long 0@Z}.k30 Dim parID As Long L.: 8qY Dim count As Integer !1/F71l DX Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double 'i4L.& Dim tlens As Double, nlens As Double -0P9|;h5 Dim curv As Double, conic As Double v4F+^0? Dim ok As Long upGLZ# TrBW0Bn>p Sub Main gKtgW&PYm ]D,\(| '用户输入对话框 mB"1QtD Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 t$rla_rbY TextBox 220,21,40,21,.TextBox1 'default: 0 (QQkXlJ Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 T@a|*.V OKButton 40,91,90,21 \;JZt[ CancelButton 190,91,90,21 S1U[{R?, Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 ,(NN)Oj TextBox 220,49,40,21,.TextBox2 'default: 4 q`UaJ_7 End Dialog KtHkLYOCG Dim dlg As UserDialog aP#/% ;3o7>yEv ok = Dialog (dlg) .aR9ulS hw=~%f; If ok=0 Then 'cancel button was pressed ER0B{b Print "Execution cancelled." W:K '2j End A#Y:VavQ? End If <,D*m+BWn |qBcE 'Assign accommodation and pupil diameter & use defaults if field left empty <,\U,jU_ If dlg.TextBox1 = "" Then "uFwsjz&B A = 0 'Default accommodation t(jE9t|2e6 Else }b/P\1#z A = CDbl(dlg.TextBox1) :aH5=@[!y End If 4issj$
Z58{YC Y If dlg.TextBox2 = "" Then <T&v\DN pupilDiam = 4 'Default pupil diameter B<0Kl.V Else !s:e pupilDiam = CDbl(dlg.TextBox2) Hz)i.AA 4 End If F~eY'~&H} 8|zOgn{ Print " " KC)}Mzt6_ Print "Accommodation = " & A & " Diopters" b`@J"E} Print "Pupil Diameter = " & pupilDiam & " mm" <_#2+7Qs E;[Uhh|78! ' Calculate new parameters with accommodation 7Gy:T47T\@ taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness Ov^##E uqLP$At Rant = 12.0 - 0.4*A 'Radius of anterior lens b'Km-'MtH CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens MdmN7> SZ}=~yoD( Rpost = -5.224557 + 0.2*A 'Radius of posterior lens V:vqt@ CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens DTSf[zP/ ~]q>}/&YLo tlens = 3.767 + 0.04*A 'Lens thickness fP\q?X@]E z+- o}i nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction 52zE -SY "%\hDL; 'Adjust parameters to account for accommodation &BRa5` D
<R_eK '************************************************************************* )Yv=:+f 'Aqueous thickness (Position of Lens) ^39lUKL '************************************************************************* cvG*p|| eID = FindFullName( "Geometry.Arizona Eye.Lens" ) r$8'1s37` GetCustomElement eID, entity *0to,$ n g5lb3`a3 parID = FindFullName( "Geometry.Arizona Eye" ) om2N*W.gk
6su~SPh ' Delete any shift(s) in z Q$v00z]f* count = 0 ~f[ Y; While GetOperationCount(eID)>count /R&h#;l GetOperation eID, count, op ]Yw$A If op.Type="ShiftZ" Then 5doi4b>]! DeleteOperation eID,count -*z7`]5J count=count-1 "r*`*1 End If oQObr count=count+1 &K{8-
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@p#m 'Set new shift in &lLfVa-l op.Type = "ShiftZ" 8-B7_GoJ+B op.val1 = taq 3%5a&b op.parent = parID ,w3-*z AddOperation eID, op "~^0 Print "Set aqueous humor thickness = " & taq-0.55 YO$D- X;N?L%Pp '************************************************************************* <r.QS[:h 'Radius and conic constant of anterior lens HE%/+mZN '************************************************************************* WFh.oe8
eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) sQac%.H;`U GetConic eID, entity, curv, conic J E7m5kTa 6{Q-]LOc[. SetConic eID, entity, 1/Rant, CCant .<F46?HS Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant #[bL9R5NC dpw-a4o} '************************************************************************* Cj<8r S4+ 'Radius and conic constant of posterior lens {;u,04OVK '************************************************************************* .8u@/f%pV eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) XFvl GetConic eID, entity, curv, conic kuD$]A
Q`& dN)8r SetConic eID, entity, 1/Rpost, CCpost 9`*Eeb> Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost jD6HCIjd' BZ1wE1 t '************************************************************************* &hI!mo 'Lens thickness (Position of posterior lens surface) ds9'k. '************************************************************************* G<n75! 7I
XWv- parID = FindFullName( "Geometry.Arizona Eye.Lens" ) 45sEhs[$ >kK@tJn ' Delete any z-shift(s) uC^)#Y\" count = 0 =g9n =spAn While GetOperationCount(eID)>count YWl#!"- GetOperation eID, count, op i[IFD]Xy!j If op.Type="ShiftZ" Then (.cA'f?h DeleteOperation eID,count 0Eb4wupo count=count-1 $jg[6`L$ End If w\o6G7 count=count+1 $t):r@L Wend B[GC@]HE -je} PwT 'Set new z-shift XNWtX-[^@ op.Type = "ShiftZ" 6r<a op.val1 = tlens Ne1Oz} op.parent = parID PJC(:R(j AddOperation eID, op ,%*UF6B
M Print "Set lens thickness = " & tlens &/]en|f" kk-<+R2 '************************************************************************* {x_.QWe5 'Lens index of refraction E(4c& '************************************************************************* .Rk8qRB eID = FindMaterial( "Lens" ) /=m AVA GetModelMaterial eID, mat z/1$G" :}zyd;Rc mat.Nd = nlens >,{sFc SetModelMaterial eID, mat hi1Ial\Y Print "Set lens index of refraction = " & nlens U]sAYp^$ dgkS5Q$/ '************************************************************************* hLLSmW( 'Pupil diameter [! $NTt_ '************************************************************************* K>$f#^ eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) uGMzU&+ noxJr/A] 'Adjust pupil diameter (trimming volume inner hole) `|ie#L(:7/ _Hv+2E[4Z SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" `s
CwgY+ z!"vez ' Adjust pupil location to just in front of the lens ~Kw#^.$3T parID = FindFullName( "Geometry.Arizona Eye" ) S\).0goOW eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) U"k$qZ[ count = 0 P"_/P8 While GetOperationCount(eID)>count smf"F\Ws GetOperation eID, count, op V%oZT>T3 If op.Type="ShiftZ" Then p"ytt|H
DeleteOperation eID,count A9MM^jV8 count=count-1 k."p& End If )@N d3Z count=count+1 .xsfq*3e5 Wend G tI )O} op.Type = "ShiftZ" e?]5q ez op.val1 = taq-0.01 *U[yeE]. op.parent = parID rL{R=0 AddOperation eID, op t5-O-AI[b{ UY< |