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Gf)3 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 Y7;=\/SV 35 L\ 模型 T[MDjhv'
I]BhkJ 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 p!DOc8a.\e Table 1. AZ眼睛模型的定义 zx@L sp eKf5orN 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. \"w+4} ElK Md 光源 2w fkXS=~6 T8d=@8g,% 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 tJmy}.t1
n%Oq"`w4 图1. 光源和提示信息使用 }KT$J G? 00@F?|-j 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 Lcf?VV}
V Ds0+RC 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 {a15s6'd 图2. 字母F光源的设定方法光 Y*IKPnPot2 E<7$!P=z` 图3. 字母F在视网膜上位置点列图 u"m TS& Z[>fFg~N4 视网膜的散射 (p]S P)LOAe1' 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 umCmxmr& z[K)0@8 6 图4. 视网膜朗伯散射设定 ,
K:d/ fYpJ2y-sA 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 YFW/
Fa\7 ^f9@=I 图5. 视网膜重点采样规格设定 N-q6_ ~+V$0Q;L 脚本 ^ E.mG> hBVm;` 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: lCTXl5J5 图6. 用户对话框的创建与编辑 ewWw 图7. 用户对话框编辑器 DQ9aq.; W8r"dK 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 uGHM ]"!) 余下的脚本计算与屈光度有关的所有参数。 yXqC 'K01"`# 分析 <PM.4B@ T Qx<lw 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 ?*ZQ:jH 图7. 字母F在视网膜上颜色分析 2cSc
8 y]+[o1]-c 脚本代码 V]m}xZ'?^ |gHdTb1 Option Explicit 'Remove this to enable non-dimensioned variables to be used. ,_s.amL3O{ %~kE,^ Dim entity As T_ENTITY _!Pi+l4p/} Dim op As T_OPERATION J8ScKMUN2 Dim mat As T_MODELMATERIAL Cl3L)
Dim A As Double t=|}?lN< Dim pupilDiam As Double _~*j=XR s Dim eID As Long 72_+ b Dim parID As Long ydj*Jy' Dim count As Integer 5NhAb$q2Y Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double W39J)~D^@ Dim tlens As Double, nlens As Double s,AJR
[ Dim curv As Double, conic As Double _+H $Pa}? Dim ok As Long f6nuh&!- hpYv*WH: Sub Main X*w;6 V =#[t!-@ '用户输入对话框 N eP Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 4'`H H TextBox 220,21,40,21,.TextBox1 'default: 0 E9Dy)f]#W Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 E1dhj3+3 OKButton 40,91,90,21 9W_mSum CancelButton 190,91,90,21 PgHmOs Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 7=Pj}x) TextBox 220,49,40,21,.TextBox2 'default: 4 BUV4L5( End Dialog {d]B+' Dim dlg As UserDialog 2oOos%0 X.FoX ok = Dialog (dlg) c5:0`~5Fn 8~~ k? If ok=0 Then 'cancel button was pressed 33wVP}e5 Print "Execution cancelled." fY?:SPR+ End 2(Yg',aMY- End If &4#%xg bg_io* K 'Assign accommodation and pupil diameter & use defaults if field left empty TTbJ9O<43 If dlg.TextBox1 = "" Then dw!Xt@,[g{ A = 0 'Default accommodation i)$+#N Else
5e1oxSU A = CDbl(dlg.TextBox1) [*I7^h% End If jTZi<
Y:bB #W
l^!)#j? If dlg.TextBox2 = "" Then a/H5Y,b> pupilDiam = 4 'Default pupil diameter 5wE6 gRJ Else J><hrZ pupilDiam = CDbl(dlg.TextBox2) fe"w--v End If Da!vGr 1zw,;m n Print " " B1s&2{L6K Print "Accommodation = " & A & " Diopters" %e)vl[:} Print "Pupil Diameter = " & pupilDiam & " mm" >Q ^ mR mG@[~w+ ' Calculate new parameters with accommodation !0|&f>y taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness L; A#N9 .6y*Z+Zg Rant = 12.0 - 0.4*A 'Radius of anterior lens z4` :n. CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens g\?07@Zd| rc7c$3# X Rpost = -5.224557 + 0.2*A 'Radius of posterior lens Eza^Tbq%j? CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens ;-l^X%r o1b.a*SZ tlens = 3.767 + 0.04*A 'Lens thickness 0(9gTxdB 4>H0a nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction e=IbEm{|
fCnwDT 'Adjust parameters to account for accommodation ,KF>@3f 2n2,MB '************************************************************************* ZCb@!V}= 'Aqueous thickness (Position of Lens) zQt)>Qx_ '************************************************************************* 7}~nQl2 eID = FindFullName( "Geometry.Arizona Eye.Lens" ) mo=@Zt GetCustomElement eID, entity ,?Vxcr UEm4):/} parID = FindFullName( "Geometry.Arizona Eye" ) dS \n2Qb yp@cn(:~ ' Delete any shift(s) in z .i*ja* count = 0 ";jAH GbO While GetOperationCount(eID)>count V~5vR`} GetOperation eID, count, op 7~ZG"^k If op.Type="ShiftZ" Then m7XN6zX DeleteOperation eID,count jGJf[:M&Pm count=count-1 /X#OX8gb] End If RU=g|TL count=count+1 EG8z&^O x Wend ;ByCtVm2 ?qn4ea-\P 'Set new shift in e%{7CR'~TD op.Type = "ShiftZ" P9Eh,j0_ op.val1 = taq {_z6 op.parent = parID '-G,7!.,r% AddOperation eID, op i12G\Ye Print "Set aqueous humor thickness = " & taq-0.55 -GQ.B{%G LUz`P6 '************************************************************************* 4"{g{8 'Radius and conic constant of anterior lens 2"P1I '************************************************************************* R iV]SgV9 eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) 73tjDO7d GetConic eID, entity, curv, conic @cm[]]f'l /jq"r-S" SetConic eID, entity, 1/Rant, CCant Qt^6w}& Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant w>Ft5"z Aqg$q* Y '************************************************************************* !4t%\N6Ib 'Radius and conic constant of posterior lens `$3P@SO" '************************************************************************* AP=SCq; eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) 09G]t1!, GetConic eID, entity, curv, conic Z vyF"4QN p{SIGpbR& SetConic eID, entity, 1/Rpost, CCpost I9U
8@e!X Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost dPgA~~ g K dNgU '************************************************************************* HDu|KW$o1 'Lens thickness (Position of posterior lens surface) lb"T'}q '************************************************************************* .Dr7YquW 6Hd^qouid parID = FindFullName( "Geometry.Arizona Eye.Lens" ) ~IQjQz? +,D82V7S ' Delete any z-shift(s) :b#5cMUe count = 0 aIWpgUd` While GetOperationCount(eID)>count l?;ReK.r GetOperation eID, count, op :n
x;~f If op.Type="ShiftZ" Then nXxnyom, DeleteOperation eID,count U2JxzHXZ count=count-1 "DJ%Yo End If J=n^&y count=count+1 T16B2|C"Y Wend xrJ0 -r0oO~KT 'Set new z-shift h 'is#X 6: op.Type = "ShiftZ" O9p^P%U " op.val1 = tlens lPl JL`e op.parent = parID Mq6_Q07 AddOperation eID, op i'#%t/ u Print "Set lens thickness = " & tlens x6=tS
q#Ik3 5 '************************************************************************* %g4)f9> 'Lens index of refraction 6|%HCxWO '************************************************************************* fK=vLcH eID = FindMaterial( "Lens" ) $>%zNq-F GetModelMaterial eID, mat |e3YTLsI "xD5>(|^+Q mat.Nd = nlens HsK52< SetModelMaterial eID, mat / pR,l5 Print "Set lens index of refraction = " & nlens 9x9E+DG#( =E8Kacu% '************************************************************************* %,) Xi 'Pupil diameter I]ol[
X0S '************************************************************************* xtp55"g eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) UX'tdB
!A yXc@i)9w3 'Adjust pupil diameter (trimming volume inner hole) 'wTJX> Je`
w/Hl/U SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" a.AEF P4N cACnBgLl ' Adjust pupil location to just in front of the lens KhbbGdmfS$ parID = FindFullName( "Geometry.Arizona Eye" ) zPb"6%1B eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) v8A{q count = 0 #Cz:l|\ i While GetOperationCount(eID)>count 2{#=Ygb0 GetOperation eID, count, op hM`*-+Zb If op.Type="ShiftZ" Then t]pJt DeleteOperation eID,count .ZH5^Sv$vp count=count-1 mHC36ba End If \Ng[lN count=count+1 %w6lNl Wend DZ|/#- k op.Type = "ShiftZ" k8"[)lDc. op.val1 = taq-0.01 o/\z4Ri)$ op.parent = parID ~bJ*LM?wOP AddOperation eID, op YA^g[, 6~q"#94 Print "Set pupil diameter = " & pupilDiam 22m'+3I~Y ia/_61% 'Update AZ Eye subassembly Description \[x4 eID = FindFullName( "Geometry.Arizona Eye" ) :~9F/Jx GetEntity eID, entity & |o V\L entity.Description = "Accommodation = " & A & "D" [x|{VJ(h SetEntity eID, entity 93#wU}) j-etEWOTr Update h%@#jvh?4 Print "DONE!" V?cUQghHg jl4rEzVu End Sub aA.TlG@zP S>p>$m,
Q 如果屈光度是4,光瞳直径是4,则会输出如下数据: L"!BN/i_ M3
$MgsN: Accommodation = 4 Diopters "A9 c] Pupil Diameter = 4 mm .c.#V:XZ#U Set aqueous humor thickness = 2.81 x;*KRO Set anterior lens radius = 10.4 and conic constant = -2.375869 _u`W$EG
L Set posterior lens radius = -4.424557 and conic constant = -3.081019 PK*
$ Set lens thickness = 3.927 D<cHa | Set lens index of refraction = 1.42672 I^6zUVH Set pupil diameter = 4 Bhrp"l
+| DONE! |