q/ d5P 人眼光学模型可用来设计眼科用设备,光学系统注定了要与人眼一起使用。本文演示了这样一个模型:Arizona眼睛模型,在Jim Schwiegerling教授的书中有详细描述:《Field Guide to Visual and Ophthalmic Optics》。AZ眼睛模型达到了基于平均临床数据所决定的轴上和轴外像差等级。FRED文件包含了此眼睛模型及几个用来分析它的光源,并包括一个基于想要的屈光度来调整模型的内嵌脚本。 wB1-|=K1 Mc#O+'](f 模型 =
C$@DNEc 110>p 模型的定义如表1种所示,由半径、圆锥常数、折射率、阿贝数、到下一面的距离等一系列表面组成。一些参数由屈光度(A)来决定。 PpJE|[] Table 1. AZ眼睛模型的定义 s= GOB"G M&}oat* 在FRED中使用0屈光度来创建的,光瞳加在了透镜的前面。材料是创建一个新的材料并选择类型“Model Material”,输入的参数是nd和vd. 7YQK@lS \gJapx( 光源 O3<Y _I^ @^XkU(m 多个光源定义来分析该模型的不同特性。图1显示了所以的光源和提示信息告诉您他们可以用来做什么。 }]n>A V{AH\IV- 图1. 光源和提示信息使用 @gu77^=' XEgx#F ;F 除了“Letter F”之外的所有光源的光线位置设定在了孔径光阑位置处,并增加了pre-propagation distance= -8。尽管光线在光瞳处创建,规定的传输方向相对于光线位置在pre-propagation distance之后。这意味着光束沿着Z轴在眼睛的前面以平行光入射,而不是在光瞳处入射。 dc\u$'F@S 2EqsfU*
I 在往下看是内置的脚本用来修改屈光度,使其为4(250mm),光源“Letter F”在视网膜处生成一个字母为F的图像。绿色的光线聚焦的非常好而红色和蓝色光线有一点的模糊。使用Positions Spot Diagram分析工具来观察最为合适。 ga2Q3mV 图2. 字母F光源的设定方法光 U4^p({\|- vxzf[ 图3. 字母F在视网膜上位置点列图 %Zv(gI`A n_xa) 视网膜的散射 Jegx[*O>b K,L> 在散射文件中,有一个名为“Retina surface”的72%的反射型朗伯散射,它为视网膜的散射提供了一个粗略的近似。为了模拟来自视网膜的散射,改变自定义元件“Eye ball” 下的视网膜的表面从“halt all” 到”Allow All”。并使几何中“plane”可追迹。 5.C[)`_ Ck/_UY| 图4. 视网膜朗伯散射设定 LBbo.KxAe3 ?V\9,BTb) 注意在视网膜的表面有散射重点采样规格定义,在“Scatter”标签的底部可获取该信息。“toward pupil”指定散射光朝向光瞳,半角度10度。 bHWvKv+ ;+TF3av0zq 图5. 视网膜重点采样规格设定 @6i8RmOu} tmY-m,U 脚本 )kY_"= d Fl 'xmz^ 内置脚本使用对话框显示屈光度和光瞳直径的数值设置。使用FRED Basic脚本创建和使用对话框非常容易。图6显示了如何获取用户自定义对话框,如下图所示: dx?njR 图6. 用户对话框的创建与编辑 D?*sdm9r` 图7. 用户对话框编辑器 ~d#;r5> VATXsD 如果“OK”按钮按下,将会核对对话框下面的代码行,如果点击取消则脚本终止。然后输入的参数赋予变量,如果此处是保留为空白,则使用默认值。因此,如果没有值输入并点击“OK”按钮,则脚本是以屈光度为0,光瞳直径为4mm来运行的。 tE9_dR^K 余下的脚本计算与屈光度有关的所有参数。 4-}A'fTU8 ad3z]dUZ9 分析 .'NO~ C$..w80/1 屈光度为4,光瞳直径为4mm,字母F点在视网膜上所成的像。 bh;b`
5 图7. 字母F在视网膜上颜色分析 thm3JfQt qY~$wVY( 脚本代码 )zL"r8si (zTI)EV Option Explicit 'Remove this to enable non-dimensioned variables to be used. /Y\E68_Fh !>kv.`|7~ Dim entity As T_ENTITY ,0<F3h Dim op As T_OPERATION :86luLFm Dim mat As T_MODELMATERIAL VqO<+~M,E Dim A As Double <cfH'~ Dim pupilDiam As Double j2{,1h j Dim eID As Long }^Ua Dim parID As Long Z\gg<Q Dim count As Integer J:-TINeB Dim taq As Double, Rant As Double, CCant As Double, Rpost As Double, CCpost As Double Q3'B$,3O^ Dim tlens As Double, nlens As Double RzY`^A6G6 Dim curv As Double, conic As Double 1KIq$lG{ E Dim ok As Long z:Zn.e*$b 7s fuju( Sub Main L};;o+5uJD U37?P7i's '用户输入对话框 #+ lq7HJ1 Begin Dialog UserDialog 320,126,"Input parameters" ' %GRID:10,7,1,1 <11Tqb TextBox 220,21,40,21,.TextBox1 'default: 0 ,,H$>r_; Text 20,21,190,21,"Accommodation (in Diopters):",.Text1,1 T~~$=vP9 OKButton 40,91,90,21 vhquHy.qi# CancelButton 190,91,90,21 []N$;~R7 Text 20,49,190,14,"Pupil diameter (4 mm default):",.Text2,1 `@.s!L(V TextBox 220,49,40,21,.TextBox2 'default: 4 *ZSp9g"Z End Dialog /%q9hI Dim dlg As UserDialog !wb~A0m ^(m6g &$( ok = Dialog (dlg) 1q233QSW) LX?r=_\ If ok=0 Then 'cancel button was pressed N5an9r&z(1 Print "Execution cancelled." \A\yuJ= End UE#Ni 5 End If lbuW*) 5iI3u 7Mn1 'Assign accommodation and pupil diameter & use defaults if field left empty ):\{n8~ If dlg.TextBox1 = "" Then _kY[8e5 A = 0 'Default accommodation 674oL, Else ch8w' A = CDbl(dlg.TextBox1) 0|> End If Qx,$)|_ 3;l>x/amk If dlg.TextBox2 = "" Then gWv+i/, pupilDiam = 4 'Default pupil diameter \/4%[Q2QDm Else tD0>(41K pupilDiam = CDbl(dlg.TextBox2) oY6|h3T=Q$ End If E+c3KqM |tJ%:`DGw Print " " MJ/%$ Print "Accommodation = " & A & " Diopters" n]fbV/ x Print "Pupil Diameter = " & pupilDiam & " mm" /uz5V/i0 <w2NJ~M^ ' Calculate new parameters with accommodation 8\.1m9&r>o taq = 0.55 + 2.97 - 0.04*A 'Aqueous thickness `rdfROKv 898wZ{ 9 Rant = 12.0 - 0.4*A 'Radius of anterior lens -hR\Y2? CCant = -7.518749 + 1.285720*A 'Conic constant of anterior lens <^'+]? I\%Lb
z Rpost = -5.224557 + 0.2*A 'Radius of posterior lens )W6-h CCpost = -1.353971 - 0.431762*A 'Conic constant of posterior lens @N_H]6z4 Qp.!U~ tlens = 3.767 + 0.04*A 'Lens thickness 6F&]Mk]V8 |Ge/|;.v` nlens = 1.42 + 0.00256*A - 0.00022*A^2 'Lens index of refraction c@#zjJhW] W#\};P
'Adjust parameters to account for accommodation "XsY~ %+B-Z/1} '************************************************************************* s]8J+8
<uO 'Aqueous thickness (Position of Lens) K/d&c] '************************************************************************* cB F%])! eID = FindFullName( "Geometry.Arizona Eye.Lens" ) (Dh;=xG GetCustomElement eID, entity E1ob+h:`d 7`<? fO parID = FindFullName( "Geometry.Arizona Eye" ) S,9WMti4x h:;eh ' Delete any shift(s) in z wR+`("2{r count = 0 V//q$/&8( While GetOperationCount(eID)>count _v=WjN GetOperation eID, count, op 9x^
/kAB If op.Type="ShiftZ" Then :O+b4R+ DeleteOperation eID,count m1o65FsY08 count=count-1 >8;%F<o2 End If
x Bw.M{ count=count+1 Y9y*":&% Wend fvMhq:Bu I%C:d#p 'Set new shift in r_sl~^* : op.Type = "ShiftZ" 0Ilvr]1a4 op.val1 = taq oqHm:u^2 op.parent = parID ;~$ $WU AddOperation eID, op 78~V/L;@S2 Print "Set aqueous humor thickness = " & taq-0.55 pz}hh^]t +9rbQ?' '************************************************************************* ZLX`[ 'Radius and conic constant of anterior lens KBHKcFk '************************************************************************* f_2^PF>? eID = FindFullName( "Geometry.Arizona Eye.Lens.Anterior" ) p)&\>
GetConic eID, entity, curv, conic QGG(I7{- 2#M:JgWV SetConic eID, entity, 1/Rant, CCant K5rj!*x.o Print "Set anterior lens radius = " & Rant & " and conic constant = " & CCant 8B+^vF
)^#Zg8L '************************************************************************* 6Q.whV%y 'Radius and conic constant of posterior lens ?o5#Ve$-X '************************************************************************* <KPx0g?=b eID = FindFullName( "Geometry.Arizona Eye.Lens.Posterior" ) Tm.w+@ GetConic eID, entity, curv, conic WR EGRy ms<u YLp SetConic eID, entity, 1/Rpost, CCpost Jd6Q 9~z# Print "Set posterior lens radius = " & Rpost & " and conic constant = " & CCpost ^F9zS`Yz2 #f;1f8yrN '************************************************************************* n7.lF 'Lens thickness (Position of posterior lens surface) Jiylrf`o '************************************************************************* >Nl~"J|]q l8us6 parID = FindFullName( "Geometry.Arizona Eye.Lens" ) O[B_7
,8?*U]} ' Delete any z-shift(s) 1U9N8{xg9 count = 0 zb,`K*Z{ While GetOperationCount(eID)>count !O_^Rn+<2 GetOperation eID, count, op ~M1%,] If op.Type="ShiftZ" Then ,?~,"IQyi[ DeleteOperation eID,count 8Kkr1}!wd count=count-1 D ,^
U%<` End If pvxqeC9` count=count+1 {j*+:Gj0V Wend *.Hnt\4| 58U[r)/ 'Set new z-shift 8k'em/M~ op.Type = "ShiftZ" qqred>K op.val1 = tlens "z4E|s op.parent = parID iqP0=(^m AddOperation eID, op W\Y
4%y} Print "Set lens thickness = " & tlens b?L43t , X]%4QIeS '************************************************************************* m]pvJJ@ 'Lens index of refraction uRhH_c-6C '************************************************************************* |.nWy"L eID = FindMaterial( "Lens" ) u)>*U'bM GetModelMaterial eID, mat B%;+8] 0k]N%!U mat.Nd = nlens |<icx8hbr SetModelMaterial eID, mat -bQvJ`iF Print "Set lens index of refraction = " & nlens 0_izTke (I
g
*iJ%2 '************************************************************************* h0}-1kVT^ 'Pupil diameter ( h,F{7 '************************************************************************* wj~8KHan eID = FindFullName( "Geometry.Arizona Eye.Pupil.Iris" ) 6
VDF@V$E ]^%3Y 'Adjust pupil diameter (trimming volume inner hole) /tP K*RRbtb SetTrimVolHole eID, pupilDiam/2, pupilDiam/2, 0, 0, "Cylinder" Ut@)<N n&&y\?n ' Adjust pupil location to just in front of the lens P~>nlm82] parID = FindFullName( "Geometry.Arizona Eye" ) +O6@)?pI eID = FindFullName( "Geometry.Arizona Eye.Pupil" ) "<b84?V5 count = 0 m!if_Iq While GetOperationCount(eID)>count !OemS7{ GetOperation eID, count, op N`fY%"5U> If op.Type="ShiftZ" Then UQr+\ u DeleteOperation eID,count 1-<Xi-=^{t count=count-1 /m:}rD End If VQ`O;n6/` count=count+1 2V 'Tt3 Wend |3@]5f& op.Type = "ShiftZ" _:
x$"i op.val1 = taq-0.01 =B2=UF op.parent = parID ZrBxEf$f AddOperation eID, op #k, kpL<a b2H6}s"=w Print "Set pupil diameter = " & pupilDiam 4 -W?u51" ~o$=(EC 'Update AZ Eye subassembly Description cd#TKmh7re eID = FindFullName( "Geometry.Arizona Eye" ) SNFz#* GetEntity eID, entity Stpho4+/y entity.Description = "Accommodation = " & A & "D" 7#QH4$@1P SetEntity eID, entity c:5BQr
' f}4h}Cq Update *z~Y *Q0
Print "DONE!" O;"%z*g. I&0yUhn End Sub =?hlgQ 5E8PbV-l 如果屈光度是4,光瞳直径是4,则会输出如下数据: ^&%?Q_] wAYc)u# Accommodation = 4 Diopters zQJbZ=5Bu" Pupil Diameter = 4 mm Qfi5fp=f Set aqueous humor thickness = 2.81 oY: "nE Set anterior lens radius = 10.4 and conic constant = -2.375869 7[\B{N9&W Set posterior lens radius = -4.424557 and conic constant = -3.081019 @VAhmYz Set lens thickness = 3.927 |v&&%>A2 Set lens index of refraction = 1.42672 xPv&(XZR Set pupil diameter = 4 ),eiJblH DONE! |